Autoradiogram of [3H]8-OH-DPAT, a 5-HT1A receptor agonist used to measure 5-HT1A receptors in vitro.

Note: Highly enriched in the superficial layers (I-II) of the cortex.

Moderate amount in deep layers (V-VI).

Absence of binding in layer IV (except in the prefrontal cortex: 2T-3T).